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Accelerator profile

Nucleate Activator

Nucleate is a student- and trainee-run nonprofit, and its Activator program forms and supports early life science and climate-bio startup teams. It brings together scientists, business trainees and early professionals around university research projects. Teams get strategy support, workshops and a Demo Day. The program is free, takes no equity, and runs through local chapters in the U.S., Canada, Europe, Israel and Australia, plus a Global Virtual Activator.

At a glance

Nucleate Activator key facts

Equity
No equity
Deal terms
Free; Nucleate takes no equity. Projects need preliminary proof-of-concept data, consent from their institution's tech transfer office, and no significant equity raised. Some chapters have offered partner funding; for example, the 2023 UK cohort received $1.65M in uncapped SAFEs from BlueYard Capital across 9 teams (third-party report).
Duration
About 8 months (October team formation to May–June Demo Day), at 5–10 hours a week
Format
Hybrid
Cohort locations
Boston, United States; Bay Area, United States; New York, United States; Los Angeles, United States; San Diego, United States; Seattle, United States; Chicago, United States; Texas, United States; New Haven, United States; Michigan, United States; Canada; United Kingdom; Germany; Switzerland; Denmark; Israel; Australia; Global Virtual
Stage
idea, pre-seed
Sectors
biotech, health, climate
Application cycle
Annual

Verified November 4, 2026 against the sources below. Terms change; confirm on the official site before applying.

Timing

Applications for the 2026–27 cohort closed October 20, 2026 (the Global Virtual Activator reportedly closed October 10; the official homepage also mentions November 1). Teams form in October 2026, strategy support starts January 2027, workshops run February to May 2027, and Demo Day is May–June 2027. Nucleate reports 303 companies incorporated and $650M raised.

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Notable alumni

  • Manifold Bio
  • Glyphic Biotechnologies
  • NextRNA

FAQ

Applying to Nucleate Activator

How much does Nucleate Activator invest?
Nucleate Activator's standard deal: Free; Nucleate takes no equity. Projects need preliminary proof-of-concept data, consent from their institution's tech transfer office, and no significant equity raised. Some chapters have offered partner funding; for example, the 2023 UK cohort received $1.65M in uncapped SAFEs from BlueYard Capital across 9 teams (third-party report).
How much equity does Nucleate Activator take?
Nucleate Activator takes no equity.
When is the Nucleate Activator application deadline?
Application cycle: Annual. Applications for the 2026–27 cohort closed October 20, 2026 (the Global Virtual Activator reportedly closed October 10; the official homepage also mentions November 1). Teams form in October 2026, strategy support starts January 2027, workshops run February to May 2027, and Demo Day is May–June 2027. Nucleate reports 303 companies incorporated and $650M raised.
Where is Nucleate Activator based?
The program runs hybrid. Cohorts run in Boston, United States, Bay Area, United States, New York, United States, Los Angeles, United States, San Diego, United States, Seattle, United States, Chicago, United States, Texas, United States, New Haven, United States, Michigan, United States, Canada, United Kingdom, Germany, Switzerland, Denmark, Israel, Australia, Global Virtual.

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